How AI-Powered MRI Enhances Early Cancer Detection With: Emi Gal

Emi Gal, Founder and CEO of Ezra, discusses the role of MRI in early cancer detection compared to liquid biopsies and blood tests. He explains that while liquid biopsies like Grail’s multi-cancer detection test have value, their sensitivity for early-stage cancer remains too low, with false negatives exceeding 80% in some cases. In contrast, imaging offers higher sensitivity and, when combined with liquid biopsies and protein biomarkers, creates the most effective screening protocol. Gal emphasizes that MRI allows not only early detection but also longitudinal monitoring of lesions, distinguishing benign from malignant growths. He argues that concerns about false positives are overstated, as most findings resolve through diagnostic follow-up. Ultimately, Gal envisions AI-powered MRI as a cornerstone of comprehensive cancer detection strategies.

About the Guest

Emi Gal is Founder, CEO, and CTO of Ezra, a healthtech company revolutionizing cancer screening with AI-enhanced MRI technology.

Notable Quote

"Bring imaging, liquid biopsies, and biomarkers together—and you get the best chance at finding cancer early."

Key Takeaways

  • Liquid biopsies alone have low sensitivity for early cancer detection
  • MRI provides higher sensitivity and enables longitudinal lesion monitoring
  • Combining imaging, blood tests, and biomarkers creates the most effective protocol

Transcript Summary

How do MRI and liquid biopsies compare in cancer detection?

Liquid biopsies have low sensitivity for early-stage cancer, while MRI provides higher sensitivity.

What’s the best approach? 

Combining imaging, liquid biopsies, and biomarkers for high sensitivity and specificity.

How does MRI handle false positives?

Most findings are resolved through diagnostic follow-up, minimizing unnecessary interventions.

About the Series

AI and Healthcare—with Mika Newton and Dr. Sanjay Juneja is an engaging interview series featuring world-renowned leaders shaping the intersection of artificial intelligence and medicine.

Dr. Sanjay Juneja, a hematologist and medical oncologist widely recognized as “TheOncDoc,” is a trailblazer in healthcare innovation and a rising authority on the transformative role of AI in medicine.

Mika Newton is an expert in healthcare data management, with a focus on data completeness and universality. Mika is on the editorial board of AI in Precision Oncology and is no stranger to bringing transformative technologies to market and fostering innovation.

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