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Clinical & Scientific Publications

  • A Scalable Method for Validated Data Extraction from Electronic Health Records with Large Language Models

    MedRxiv (2025)

  • Kinome reprogramming of G2/M kinases and repression of MYCN contribute to superior efficacy of lorlatinib in ALK-driven neuroblastoma

    Molecular Cancer Therapeutics (2025)

  • Gemcitabine / Oxaliplatin / Lenvatinib (GEMOX-Len) for refractory, relapsed or unresectable fibrolamellar carcinoma

    AGITG Annual Scientific Meeting (2024)

  • Overall Survival and Quality of Life of Glioblastoma Patients According to MGMT Methylation Status: Real- World Data Analysis

    Poster at ISPOR EU (2024)

  • Leveraging real-world data from multiple institutions to assess the rate of bilateral mastectomy after cancer genetics evaluations with genetic counselors.

    Abstract at ASCO (2024)

  • Leveraging real-world data from multiple institutions to assess uptake of risk-reducing salpingo-oophorectomy after cancer genetic counseling

    NSGC Annual Conference (2024)

  • A Health Care Clinical Data Platform for Rapid Deployment of Artificial Intelligence and Machine Learning Algorithms for Cancer Care and Oncology Clinical Trials

    North Carolina Medical Journal (2024)

  • xPedite: A Study to Expedite DIPG and DMG research

    Poster at ISPNO (2024)

  • Leveraging real-world data from multiple institutions to assess the rate of bilateral mastectomy after cancer genetics evaluations with genetic counselors

    Abstract at ASCO (2024)

  • Use of a nationwide, patient-powered observational platform to define the landscape of treatment, molecular profiling, and outcomes for fibrolamellar carcinoma

    Abstract at ASCO (2024)

  • Proton pump inhibitors are detrimental to overall survival of patients with GBM: results from a nationwide Real-World Evidence database

    Neuro-Oncology Practice (2024)

  • An atlas of causal and mechanistic drivers of interpatient heterogeneity in glioma

    MedRxiv (2024)

  • Efficacy of immune checkpoint inhibitors in glioblastoma from real world data analysis

    Poster at SNO (2023)

  • AI-Augmented Clinical Decision Support in a Patient-Centric Precision Oncology Registry

    AI in Precision Oncology (2023)

  • Tumor Treating Fields: Real-World Survival and Quality of Life Outcomes on the XCELSIOR Platform

    Neuro-Oncology (2023)

  • Clinical utility of an international multidisciplinary virtual tumor board for fibrolamellar carcinoma.

    Abstract at ASCO 2023

  • Use of proton pump inhibitors (PPI) in glioblastoma (GBM) and relationship to overall survival in a national real-world evidence (RWE) database.

    Abstract at ASCO 2023

  • Real-World Quality-of-Life and Health Utilities for Patients with CNS Cancers on the xCELSIOR Platform

    Neuro-Oncology (2022)

  • Updated clinical outcomes from ULI-EAP-100, an intermediate expanded access program for ulixertinib (BVD-523)

    Journal of Clinical Oncology (2022)

  • Systems biology based therapeutic predictions with gbmSYGNAL and clinical correlates in the real world longitudinal outcomes registry XCELSIOR

    Poster at SNO (2022)

  • Virtual Trials: Causally-validated treatment effects efficiently learned from an observational brain cancer registry

    Artificial Intelligence in Medicine (2022)

  • Real world clinical outcomes of patients with diffuse midline glioma in a longitudinal outcomes registry

    Poster at SNO (2022)

  • Case report: response to the ERK1/2 inhibitor ulixertinib in BRAF D594G cutaneous melanoma

    Melanoma Research (2022)

  • Application of XCELSIOR, a nationwide real-world observational research protocol, to identify efficacious targeted therapy regimens in advanced pancreatic adenocarcinoma.

    Abstract at ASCO (2022)

  • Cancer Commons’ Virtual Tumor Board program- a patient-centric advisory panel and Real-World Data registry.

    Poster at ASCO GI (2022)

  • XCELSIOR: A real-time, real-world learning platform for patients with advanced cancer.

    Poster at SNO Meeting (2021)

  • Use of a real-world data registry to rapidly generate outcomes data following a case study of a novel treatment combination in pancreatic adenocarcinoma

    Poster at AACR (2020)

  • A Multilevel Model for Precision Oncology

    Poster at ProgProb (2020).

  • Is Cancer Solvable? Towards Efficient and Ethical Biomedical Science

    In the Journal of Law, Medicine & Ethics (2019).

  • Prototyping a precision oncology 3.0 rapid learning platform

    In BMC Bioinformatics (2018).

  • Paths to Precision Medicine

    In the Journal of Precision Medicine (2015).

  • Rapid learning for precision oncology

    In Nature Reviews Clinical Oncology (2014).

  • Theoretical Issues for Global Cumulative Treatment Analysis (GCTA)

    In arXiv (2013).

  • A novel classification of lung cancer into molecular subtypes

    In PLOS One (2012).

  • A melanoma molecular disease model

    In PLOS One (2011).

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